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Role of Epigenetic Changes in the Etiology of Human Diseases

Introduction The field of epigenetics is ever-growing and considered to be a relatively new branch of genetic research. However, the concept dates back to the 1940s when it was understood as a mechanism that involved gene and gene-product interactions responsible for phenotypic expression1. Epigenetics is now understood as stable, heritable changes in gene expression that are not associated with changes in the actual DNA sequence. That means that the phenotype…

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