Understanding of protein-DNA interactions is critical for the studying of many biological processes. Specifically, interactions of DNA with transcription factors and chromatin-associated proteins are important for understanding of gene expression and phenotype-influencing mechanisms.
The Illumina Whole-Genome Chromatin IP Sequencing (ChIP-Seq) application allows researchers to identify bindings using genome-wide, massively parallel sequence analysis methods. This approach allows the quantification of binding sites – any Chip-able proteins such as transcription factors, polymerases and transcriptional machinery, structural proteins, protein modifications, and DNA modifications
Macrogen Clinical Laboratory offers this powerful approach, and will provide consultation to our clients and guide them through the design of the experiments.