Macrogen Corp. RNA / Transcriptome Sequencing Services

Sequencing

transcriptome sequencing

Macrogen Corp. offers high-quality RNA sequencing services, also called transcriptome sequencing. Our state-of-the-art automated sequencing reduces the turnaround time for researchers at low prices, yet retains the highest levels of quality.

Our RNA / transcriptome sequencing methods are reliable, fast, and cost-effective. We also provide bioinformatics services regarding differentially expressed genes, fusion genes, post-translation modification of specific mRNA transcripts, and more.

Macrogen Corp. offers RNA / transcriptome sequencing services for researchers in the United States and around the globe.

What Is RNA / Transcriptome Sequencing?

A transcriptome is a collection of all the transcripts present in a given cell. The sequence of an RNA mirrors the sequence of the DNA from which it was transcribed. Consequently, by analyzing the entire collection of RNAs or transcriptomes in a cell, researchers can determine when and where each gene is turned on or off in the cells and tissues of an organism.

RNA sequencing can give researchers more visibility into previously undetected changes that can occur in certain states of diseases. Researchers can also see more details about how a transcriptome reacts to certain therapeutics, environmental situations, or other conditions.

With RNA sequencing, researchers can discover more about a transcriptome in just one assessment, including new and existing qualities. RNA sequencing can detect alternative gene spliced transcripts, gene fusion, mutations and variants, post-transcriptional modifications, and other gene expressions.

As DNA sequencing technology advances, RNA / transcriptome sequencing has become more cost-effective and more widely available. This increase in usage has made RNA sequencing an excellent tool for RNA editing, RNA profiling, and allele-specific expression.

Macrogen Corp. RNA / transcriptome sequencing services include the following:

  •         Transcript isoform discovery and their validation
  •         Coding and annotation with SNPs
  •         Profiling and characterization junctions
  •         Quantitative determination and identification of regulatory transcripts

Types of RNA / Transcriptome Sequencing

Researchers utilize many different methods of RNA / transcriptome sequencing to identify existing and novel types of gene expression. At Macrogen Corp., we use only the most advanced industry-standard methods, including the following:

  • mRNA Sequencing: This type of RNA sequencing is one of most popular methods for analyzing disease states and biological processes in the study of transcriptomes. This method is extremely in-depth, allowing researchers to find new genes that were previously imperceptible.
  • Small RNA Sequencing: This type of sequencing targets and isolates small RNA, including microRNA, to discover how noncoding RNA affects different types of gene expressions.
  • Whole RNA Sequencing: Whole RNA sequencing is a comprehensive method that aims to accurately measure the amount of genes and transcripts in the transcriptome. It identifies existing and novel coding and noncoding RNA.
  • Targeted RNA Sequencing: This sequencing method focuses on two different types of targeted transcriptome assessment: targeted enrichment and targeted amplicon.
  • RNA Exome Capture Sequencing: This method of RNA sequencing identifies different types of the RNA exome by examining specific regions of RNA coding.
  • Single-Cell RNA Sequencing: This type of RNA sequencing studies individual cells, specifically the transcriptomes and genomes. This allows researchers to examine the small complexities of each region of a transcriptome.

Benefits of RNA / Transcriptome Sequencing

RNA sequencing can be extremely valuable for patients. Because this form of sequencing does not require prior knowledge about the transcript, it can identify information that might be overlooked by other methods.

Combined with next-generation sequencing, RNA sequencing is commonly used by researchers. This form of sequencing carries many benefits for hospitals and clinics:

  •         Captures both previously known and novel transcriptome features
  •         Provides close, accurate studies of a variety of gene expression
  •         Offers accurate results often at a lower price point per sample

RNA / transcriptome sequencing is one of the most advanced forms of sequencing in the industry, and is widely regarded as the future of transcriptomics. Not only is RNA / transcriptome sequencing currently transforming industry research, but it is also transforming the way we view transcriptomes themselves.

RNA sequencing is extremely precise in measuring transcripts and identifying complexities. It can more accurately determine gene expressions than many other methods of arrays. This is precisely why Macrogen Corp. offers RNA / transcriptome sequencing services. This method of sequencing is the future of transcript research, and can be extremely beneficial for hospitals and clinics around the world.

Since 1997, Macrogen Corp. has led the industry in innovation and quality, and we look forward to extending our expertise in next-generation sequencing techniques to our clients.

Also available as Cli-Seq.

About Macrogen Corp.

Macrogen Corp. was founded to provide clinical sequencing services to hospitals and clinics in the United States and around the world. As one of the world’s leading bioscience research firms, Macrogen Corp. has a proven commitment to delivering the most advanced RNA / transcriptome sequencing solutions. Our goal is to use the most cutting-edge, advanced technology available to further important genetic research, paving the way for groundbreaking scientific discoveries.

Contact Macrogen Corp. to learn more about our RNA / transcriptome sequencing services, or call us at (301) 683-5040.

 

Contact Us About Transcriptome / RNA Sequencing Services.