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Next-Generation Sequencing: Popular Applications in Clinical Medicine

Introduction and Brief overview of NGS An important technological advance in the practice of diagnostic and clinical medicine is next-generation sequencing (NGS). This technology is rapidly transforming clinical practice by providing a means to obtain both diagnostic and prognostic data with the same data. This transformation is made possible because of the cost-effective and rapid nature of NGS.   Next-generation sequencing is a massive parallel sequencing method allowing the sequencing…

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Are You DNA Smart? Take the Quiz!

Introduction and Key Definitions Deoxyribonucleic acid (DNA) is the blueprint that contains the instructions for cells (and thus an organism) to function. This includes for reproduction, growth, maintenance, and all other functions that sustain life. This role of DNA is mediated through what is called the central dogma. In the basic sense, DNA codes for RNA that subsequently codes for proteins. An exception to this is the case of some…

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The Top 5 Next Generation Sequencing (NGS) Forums and Communities

Next Generation Sequencing (NGS) has seen massive growth as the demand for low-cost sequencing has exploded. Information on NGS, though, is highly technical, and it’s important to go to the right sources to discuss the varying technologies in the field. These are the top 5 Next Generation Sequencing forums in 2016:   SEQanswers SEQanswers is a forum dedicated specifically to the topic of Next Generation Sequencing. It takes up the…

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DNA Sequencing Uncovers New Variant of Diabetes

DNA Sequencing and Medical Discovery Diagnostic Applications The ability to rapidly know the exact cause of an ailment or disease is the first and often a difficult challenge in the path to recovery.  A symptom or set of symptoms can point to a number of different conditions. Diagnostic approaches are employed to decipher the historical and symptom information. However, there are many diagnostic approaches that still do not unequivocally reveal…

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Macrogen Corp Announced as precision FDA Participating Provider

Macrogen Corp., one of the leading providers of next-generation sequencing services, has been announced as a participating provider in precisionFDA. The precisionFDA web platform is part of President Obama’s vision with his Precision Medical Initiative announced last year. The administration’s goal is to move away from a “one-size-fits-all” approach to medicine and move towards a personalized medicine approach that takes into account differences in people’s genes, environments, and lifestyles. The…

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The Top Five Genome Conferences In The World

The emergence and growth of whole genome sequencing technologies, and the resulting immense database generated, requires that scientists and medical professionals learn more about the powerful tools available to them. These tools give scientists the ability to interpret and apply the information and are becoming increasingly available. Genomic technologies have bolstered the power of personalized medicine and are facilitating drug discovery. A plethora of genomic conferences that focus on a…

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Macrogen Provides Patient-Specific Interpretation for the Launch of New Clinical Next-Generation Sequencing Panels

Macrogen has recently partnered with N-of-One, a leader in clinical interpretation, with the goal of delivering high-level clinical interpretation for its newly launched clinical next-generation sequencing panels. N-of-One enables laboratories to save time and money while scaling their molecular diagnostics programs. It also provides therapeutic options to client organizations for thousands of cancer patient cases. With this partnership, Macrogen’s Next Generation Sequencing technology not only makes it possible to process,…

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Managing High-Throughput DNA Sequencing Data

Introduction The newest sequencing technologies are providing new insights into disease etiology, individual susceptibilities, keys to drug discovery, and more. However, there are many questions and challenges regarding how to understand the meaning and applicability of the newfound wealth of data. As new data is generated at record rates, scientists are working diligently on the development of methods to archive the massive sequencing information and create bioinformatics tools to analyze…

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Macrogen Completes Merger of US Affiliates to Become Macrogen Corp.

Merger will help Macrogen Corp. eliminate redundant R&D and business costs and provide a unified clinical diagnosis service   Recently, biotechnology and precision medicine firm Macrogen merged a trio of its U.S. based affiliates. The move will effectively align the affiliates behind the company’s core mission: Precision medical research and clinical diagnosis. Now, Macrogen Corporation – the surviving entity of the merge – will include: Macrogen Corp Macrogen Clinical Laboratory…

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DRAGEN Processor

Macrogen Deploys Advanced Data Processors for Faster Analysis of Large-Scale Genomic and Sequencing Data

Macrogen recently partnered with Edico Genome to reinforce its Bio-IT infrastructure with new DRAGEN processors. By deploying several DRAGEN Bio-IT Processors, which are designed and manufactured by Edico Genome, Macrogen will be able to provide faster processing and analysis of high-throughput NGS data. Accurate DNA sequencing and genomic analysis is reliant on advanced technology. To this end, clinicians and researchers use powerful processors and collection instruments to capture and analyze…

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